Publication

CRISPR/Cas9 technology

Mouse:

Dr. Matt Merrins

β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the KATP channel (Aug, 2022)

Dr. Bradfield (Oncology)

Generation of an Allelic Series at the Ahr Locus Using an Edited Recombinant Approach(April, 2021)

Dr. Svaren (Comparative Biosciences, Waisman Center)
Pmp22 super-enhancer deletion causes tomacula formation and conduction block in peripheral nerves (June 2020).

Dr. Pike (Biochemistry)
Mechanistic homeostasis of vitamin D metabolism in the kidney through reciprocal modulation of Cyp27b1 and Cyp24a1 expression (Febuary 2020).

Dr. Bresnick (TALENs, Cell & Regenerative Biology)
GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia (August 2017).

Rats:

Dr. Jon Audhya

TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance (September, 2022)

Dr. Chesler (Engineering)

17β-Estradiol and estrogen receptor α protect right ventricular function in pulmonary hypertension via BMPR2 and apelin(January, 2021)

Assisted Reproductive Technology

Dr. Jorgensen (Comparative Bioscience, SVM)
IRX3 and IRX5 Collaborate During Ovary Development and Follicle Formation to Establish Responsive Granulosa Cells in the Adult Mouse (June 2020).

Dr. Davis (Endocrinology, Medicine)
Successful in vitro fertilization and generation of transgenics in Black and Tan Brachyury (BTBR) mice.(December, 2016).

Dr. Bradfield (Oncology)
Loss of BMAL1 in ovarian steroidogenic cells results in implantation failure in female mice. (September, 2014).